Eye wrinkles, nasolabial folds or crow’s feet are expression lines that appear as a consequence of natural aging.
De Felipe Dermatology Clinic, has studied carefully how to eliminate wrinkles on the face. Our specialists in anti-aging medicine will help you to achieve a young and natural appearance with different treatments as well as the use of botulinum toxin in London.
What is Botulinum Toxin?
Botulinum toxin is a relatively small protein that penetrates nerve endings, those that stimulate muscles or sweating glands. Muscle contraction is smoothened in those places where botulinum toxin is injected and dynamic wrinkles and lines are reduced. Its correct name is botulinum neurotoxin type A (BNTA).
BNTA in its pure form is wrapped in several different proteins, among which are mostly hemagglutinins or HA. These are made inside some bacteria in laboratories. Each pharmaceutical company has its own way of obtaining BNTA together with these HA. Therefore, each botulinum toxin has its own composition and is formed by a slightly different molecular composition and weight. This explains why each laboratory gives a different name to these compounds. De Felipe Dermatology Clinic experts have been working in the advisory board of some of these pharmaceutical companies and delivering training and performing research for many years.
Types of botulinum toxin type A
There are different types of botulinum neurotoxin type A. Despite the fact that they all contain in its core the same molecule, their final composition differs from one another. These changes have an impact in several aspects that we must take into account.
OnabotulinumtoxinA
The complex formed by this type of neurotoxin is 900 kd in size, of which 150 is the neurotoxin itself (BNTA) and the rest are protein compounds. It should be stored in between 2-8ºC and can be stored for two years.
AbobotulinumtoxinA
They are formed by a 500 kd protein complex that has no therapeutic function but reduces its ability to migrate. It should be kept between 2-8ºC and can be stored for 2 years.
IncobotulinumtoxinA
No load of complexing proteins. Significantly reduces the risk of production of neutralizing antibodies. It does not require cold storage but can stay at room temperature for three years.
PrabotulinumtoxinA
With a size of 150 kd, this type of toxin is injected no more than every 3 months.
Botulinum toxin treatment London
Wrinkle treatment in the Dermatology Clinic in London is performed on an outpatient basis, it does not require prior anesthesia and recovery is immediate.
What does the treatment consist of?
Wrinkle treatment in London with botulinum toxin consists of introducing a minimal amount of the product into the skin with a very fine needle, very superficially, in the area where there are facial expression wrinkles such as the crow’s feet, the glabella lines or the forehead.
Botulinum toxin is stored in a small sterile glass container. The Doctor dilutes it with a little physiological saline solution making it ready for injection. A small 30g needle is injected to minimize damage into several points of the skin, under which the muscles to be relaxed are located.
If the patient finds the procedure painful, a little bit of topical anesthesia for 15 or 20 minutes can be applied, but that’s rarely required for a procedure that otherwise lasts one or two minutes.
Procedure duration
15 minutes
Type of anesthesia
Does not require
Clinical result
To be seen, from 1 to 2 weeks.
Recovery time
Immediate
Results last for
From 3 to 6 months
Wrinkles before and after
No change is observed Immediately after the treatment.
Botulinum toxin does not start to work until the fifth day after the injection. However, the patient can resume his work and social life without any delay. A small bruise might rarely appear in the treated area but disappears shortly after. Expression are reduced and the result is a natural and relaxed face.






Patients ask
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